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DeSoto, MO Weather Forecast
DeSoto, MO Weather Forecast Date: 1228 PM CST Thu Nov 05 2026
The area/counties/county of: Saint Francois County Mo, including the city of Farmington.or toggle through each period.
This Afternoon... Sunny. Highs in the mid 60s. West winds 5 to 10 mph with gusts up to 20 mph.
Tonight... Partly cloudy in the evening, then mostly cloudy with patchy very light drizzle after midnight. Lows in the mid 40s. Northwest winds around 5 mph.
Friday... Mostly cloudy with patchy very light drizzle in the morning, then mostly sunny in the afternoon. Cooler with highs in the lower 50s. North winds 5 to 10 mph.
Friday Night... Clear, cooler with lows around 30. North winds around 5 mph in the evening, becoming light and variable.
Saturday... Mostly sunny. Highs in the mid 50s. North winds around 5 mph.
Saturday Night... Mostly clear. Lows around 30.
Sunday... Clear. Highs in the lower 60s. Lows in the lower 30s.
Sunday Night... Clear. Highs in the lower 60s. Lows in the lower 30s.
Monday... Clear. Highs in the upper 60s. Lows in the mid 30s.
Tuesday... Clear. Highs in the upper 60s. Lows in the mid 30s.
POP = Probability of Precipitation
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